Umphumela we-bactericidal we-hyperbaric oxygen therapy ekulimaleni kokushiswa

Isingeniso

Ukulimala kokushiswa kuvame ukuhlangana nezimo eziphuthumayo futhi kuvame ukuba indawo yokungena yamagciwane.Izingozi zokusha ezingaphezu kuka-450,000 zenzeka minyaka yonke okubangela ukufa kwabantu abacishe babe yi-3,400 e-United States.Ukusabalala kokulimala kokusha e-Indonesia kungama-0.7% ngo-2013. Ingxenye engaphezu kwengxenye yalokhu Ngokwezifundo eziningana ezimayelana nokusetshenziswa kweziguli zelashelwa izifo ezibangelwa amagciwane, ezinye zazo ezazingazweli kuma-antibiotic athile.Ukusebenzisai-hyperbaric oxygen therapy(HBOT) ukwelapha ukusha kunemiphumela emihle eminingana ehlanganisa nokuphatha izifo ezibangelwa amagciwane, kanye nokusheshisa inqubo yokuphola kwesilonda.Ngakho-ke, lolu cwaningo luhlose ukufakazela ukuphumelela kwe-HBOT ekuvimbeleni ukukhula kwamagciwane.

Izindlela

Lolu ucwaningo locwaningo lokuhlola onogwaja kusetshenziswa idizayini yeqembu lokulawula ngemuva kokuhlolwa.onogwaja abangu-38 banikezwe ukushiswa kwe-second-degree esifundeni sehlombe nge-iron plate yensimbi eye yashiswa ngaphambilini imizuzu emi-3.Amasiko amagciwane athathwe ngezinsuku ezi-5 nezi-10 ngemuva kokuchayeka ekushiseni.Amasampula ahlukaniswe ngamaqembu amabili, i-HBOT nokulawula.Ukuhlaziywa kwezibalo kwenziwa kusetshenziswa indlela ye-Mann-Whitney U.

Imiphumela

Amagciwane e-Gram-negative ayeyi-pathogen etholakala kakhulu kuwo womabili amaqembu.I-Citrobacter freundi kwakuyibhaktheriya evame kakhulu e-Gram-negative (34%) etholakala emiphumeleni yesiko lamaqembu womabili.

Ngokuphambene neqembu lokulawula, kwakungekho ukukhula kwebhaktheriya okutholakala emiphumeleni yesiko leqembu le-HBOT, (0%) vs (58%).Ukunciphisa okuphawulekayo kokukhula kwebhaktheriya kubonwe eqenjini le-HBOT (69%) uma kuqhathaniswa neqembu lokulawula (5%).Amazinga ebhaktheriya amile konogwaja abayisi-6 (31%) eqenjini le-HBOT kanye nonogwaja abangu-7 (37%) eqenjini elilawulayo.Sekukonke, kwakukhona ukukhula kwamagciwane okuncane kakhulu eqenjini lokwelapha i-HBOT uma kuqhathaniswa neqembu lokulawula (p <0.001).

Isiphetho

Ukuphathwa kwe-HBOT kunganciphisa kakhulu ukukhula kwamagciwane ekulimaleni kokushiswa.