Ukunciphisa Ubuhlungu Okungapheli: Isayensi Engemuva Kwe-Hyperbaric Oxygen Therapy

Izindlela Ezingemuva Kwe-Hyperbaric Oxygen Therapy for Pain Relief

1. Ukuthuthukiswa Kwezimo Ze-Hypoxic

Izimo eziningi ezibuhlungu zihlotshaniswa ne-hypoxia yezicubu zendawo kanye ne-ischemia. Endaweni ye-hyperbaric, okuqukethwe kwe-oxygen egazini kukhula kakhulu. Ngokuvamile, igazi le-arterial linokuqukethwe kwe-oksijini okungaba ngu-20 ml/dl; kodwa-ke, lokhu kungase kukhuphuke ngokuphawulekayo esimisweni se-hyperbaric. Amazinga oksijini aphakeme angasakazekela ezicutshini ze-ischemic ne-hypoxic, athuthukise ukutholakala komoyampilo futhi anciphise ukunqwabelana kwemikhiqizo ye-acidic metabolism ebangela ubuhlungu.

Izicubu ze-neural zizwela kakhulu ku-hypoxia. Ukwelashwa kwe-oxygen ye-Hyperbaric kwandisa ingcindezi yengxenye ye-oksijini ezicutshini ze-neural, kuthuthukisa isimo se-hypoxic sezintambo zezinzwa kanye ukusiza ekulungiseni nasekubuyiseleni ukusebenza kwezinzwa ezilimele, njengokulimala kwenzwa ye-peripheral, lapho ingasheshisa ukulungiswa kwe-myelin sheath futhi inciphise ubuhlungu obuhambisana nokulimala kwezinzwa.

2. Ukwehliswa Kwempendulo Evuvukalayo

Ukwelashwa kwe-oxygen ye-hyperbaric kungasiza ukulinganisa amazinga ezici ezivuthayo ezifana ne-interleukin-1 kanye ne-tumor necrosis factor-alpha emzimbeni. Ukuncishiswa kwezimpawu zokuvuvukala kunciphisa ukugqugquzelwa kwezicubu ezizungezile futhi kamuva kudambise ubuhlungu. Ngaphezu kwalokho, umoya-mpilo we-hyperbaric ucindezela imithambo yegazi futhi unciphise ukugeleza kwegazi lendawo, wehlise ukungeneka kwe-capillary futhi ngaleyo ndlela unciphise i-edema yezicubu. Isibonelo, ezimeni zokulimala kwezicubu ezithambile ezidabukisayo, ukunciphisa i-edema kungadambisa ingcindezi eziphethweni zezinzwa ezizungezile, kuqhubeke nokunciphisa ubuhlungu.

3. Ukulawulwa Kokusebenza Kwesistimu Yezinzwa

Ukwelashwa kwe-oxygen ye-hyperbaric kungalawula injabulo yesimiso sezinzwa esizwelayo, ukuthuthukisa ithoni ye-vascular nokunciphisa ubuhlungu. Ukwengeza, ingase ikhuthaze ukukhululwa kwama-neurotransmitters afana nama-endorphin, anezinto ezinamandla zokudambisa izinhlungu, okunomthelela ekwehleni kombono wobuhlungu.

 

Izicelo ze-Hyperbaric Oxygen Therapy in Pain Management

1. Ukwelashwa kweI-Complex Regional Pain Syndrome(CRPS)

I-CRPS ibonakala ngobuhlungu obukhulu, ukuvuvukala, kanye nezinguquko zesikhumba njengesimo sesistimu esingapheli. I-hypoxia kanye ne-acidosis ehambisana ne-CRPS kuqinisa ubuhlungu futhi kunciphise ukubekezelela ubuhlungu. Ukwelashwa kwe-oxygen ye-Hyperbaric kubangela imvelo ephezulu ye-oksijeni engakwazi ukubopha imikhumbi, inciphise i-edema, futhi ithuthukise ingcindezi ye-oxygen yezicubu. Ngaphezu kwalokho, ivuselela umsebenzi wama-osteoblasts acindezelwe, inciphisa ukwakheka kwezicubu ze-fibrous.

2. Ukuphathwa kweI-Fibromyalgia 

I-Fibromyalgia yisimo esingachazeki esaziwa ngobuhlungu obusakazekile kanye nokungakhululeki okukhulu. Ucwaningo luye lwabonisa ukuthi i-hypoxia yendawo inomthelela ekushintsheni okuwohlokayo emisipha yeziguli ze-fibromyalgia. I-Hyperbaric oxygen therapy

kwandisa ukugxila komoyampilo ezicutshini ngaphezu kwamazinga okuphila, ngaleyo ndlela kuphule umjikelezo we-hypoxic-pain futhi kunikeze ukukhululeka kobuhlungu.

3. Ukwelashwa kwe-Postherpetic Neuralgia

I-postherpetic neuralgia ihlanganisa ubuhlungu kanye/noma ukulunywa okulandelayo. Ucwaningo lubonisa ukuthi i-hyperbaric oxygen therapy inciphisa ubuhlungu nokucindezeleka kwamaphuzu ezigulini eziphethwe yilesi simo.

4. Ukukhululwa kweUbuhlungu be-Ischemic Emaphethelweni Aphansi 

I-atherosclerotic occlusive disease, i-thrombosis, nezimo ezihlukahlukene ze-arterial ngokuvamile ziholela ebuhlungu be-ischemic ezithweni. Ukwelashwa kwe-oxygen ye-hyperbaric kunganciphisa ubuhlungu be-ischemic ngokunciphisa i-hypoxia ne-edema, kanye nokunciphisa ukuqoqwa kwezinto ezibangela ubuhlungu ngenkathi kuthuthukisa ukuhambisana kwe-endorphin-receptor.

5. Ukunciphisa I-Trigeminal Neuralgia

Ukwelashwa kwe-oxygen ye-hyperbaric kuye kwaboniswa ukunciphisa amazinga obuhlungu ezigulini ezine-neuralgia ye-trigeminal futhi kunciphise isidingo se-analgesics yomlomo.

 

Isiphetho

Ukwelashwa kwe-oxygen ye-hyperbaric kubonakala njengendlela yokwelapha ephumelelayo yobuhlungu obungapheli, ikakhulukazi lapho izindlela zokwelapha ezivamile zihluleka. Indlela yayo ehlukahlukene yokuthuthukisa ukutholakala komoyampilo, ukunciphisa ukuvuvukala, kanye nokulinganisa imisebenzi ye-neural kwenza kube inketho ephoqelelayo ezigulini ezidinga ukukhululeka kobuhlungu. Uma uhlushwa ubuhlungu obungapheli, cabanga ukuxoxa nge-hyperbaric oxygen therapy njengendlela entsha yokwelapha engaba khona.