Ucwaningo lwakamuva luhlole imiphumela yokwelashwa komoya-mpilo we-hyperbaric ekusebenzeni kwenhliziyo kwabantu abane-COVID ende, ebhekisa ezindabeni zezempilo ezahlukahlukene eziqhubekayo noma eziphindaphindayo ngemuva kokutheleleka kwe-SARS-CoV-2.
Lezi zinkinga zingabandakanya isigqi senhliziyo esingavamile kanye nengozi eyengeziwe yokungasebenzi kahle kwenhliziyo nemithambo yegazi.Abacwaningi bathole ukuthi ukuhogela umoya-mpilo ocindezelwe kakhulu, ohlanzekile kungasiza ekuthuthukiseni ukufinyela kwenhliziyo ezigulini ezinde ze-COVID.
Lolu cwaningo beluholwa nguSolwazi Marina Leitman waseSackler School of Medicine eNyuvesi yaseTel Aviv kanye naseShamir Medical Center kwa-Israel.Nakuba lokhu okutholakele kwethulwe engqungqutheleni ngoMeyi 2023 eyayibanjwe yi-European Society of Cardiology, akukahlolisiswa ontanga.
I-COVID ende nokukhathazeka kwenhliziyo
I-COVID ende, ebizwa nangokuthi yi-post-COVID syndrome, ithinta cishe u-10-20% wabantu abake baba ne-COVID-19.Ngenkathi abantu abaningi belulama ngokugcwele kuleli gciwane, i-COVID ende ingatholakala lapho izimpawu ziqhubeka okungenani izinyanga ezintathu ngemuva kokuqala kwezimpawu ze-COVID-19.
Izimpawu ze-COVID ende zifaka phakathi izindaba ezihlukene zempilo, okuhlanganisa ukuphelelwa umoya, ubunzima bokuqonda (okubizwa ngokuthi inkungu yobuchopho), ukudangala, kanye nezinkinga eziningi zenhliziyo nemithambo yegazi.Abantu abane-COVID ende basengozini enkulu yokuba nesifo senhliziyo, ukwehluleka kwenhliziyo, nezinye izimo ezihlobene.
Ngisho nabantu ababengenazo izinkinga zenhliziyo zangaphambilini noma abasengozini enkulu yokuba nesifo senhliziyo bake bahlangabezana nalezi zimpawu, njengoba kuboniswe ucwaningo olwenziwa ngo-2022.
Izindlela zocwaningo
UDkt. Leitman kanye nozakwabo baqasha iziguli ezingama-60 ezazinezimpawu zesikhathi eside ze-COVID-19, ngisho nangemva kwamacala athambile kuya kwamaphakathi, ahlala okungenani izinyanga ezintathu.Leli qembu lalihlanganisa abantu abalaliswe esibhedlela nabangekho esibhedlela.
Ukuze benze ucwaningo lwabo, abacwaningi bahlukanise abahlanganyeli babe ngamaqembu amabili: eyodwa ithola i-hyperbaric oxygen therapy (HBOT) kanti enye ithola inqubo yokulingisa (sham).Isabelo senziwa ngokungahleliwe, ngenani elilinganayo lezifundo eqenjini ngalinye.Phakathi namasonto ayisishiyagalombili, umuntu ngamunye wayenezikhathi ezinhlanu ngesonto.
Iqembu le-HBOT lithole i-oksijini engu-100% ngokucindezela kwe-atmospheres engu-2 imizuzu engu-90, ngamakhefu amafushane njalo ngemizuzu engu-20.Ngakolunye uhlangothi, iqembu le-sham lithole i-21% oksijini ngokucindezela komkhathi we-1 isikhathi esifanayo kodwa ngaphandle kokuphumula.
Ukwengeza, bonke abahlanganyeli bathola i-echocardiography, ukuhlolwa kokuhlola umsebenzi wenhliziyo, ngaphambi kweseshini yokuqala ye-HBOT kanye ne-1 kuya kumaviki angu-3 ngemva kweseshini yokugcina.
Ekuqaleni kocwaningo, ababambiqhaza abangama-29 kwabangu-60 babenenani elijwayelekile le-global longitudinal strain (GLS) elingu-17.8%.Phakathi kwabo, abangu-16 babelwa eqenjini le-HBOT, kanti abangu-13 abasele babeseqenjini lomgunyathi.
Imiphumela yocwaningo
Ngemuva kokwelashwa, iqembu lokungenelela lathola ukwanda okuphawulekayo kwesilinganiso se-GLS, esifinyelela ku-20.2%.Ngokufanayo, iqembu le-sham nalo libe nokukhuphuka kwesilinganiso se-GLS, esifinyelele -19.1%.Kodwa-ke, isilinganiso sangaphambili kuphela esibonise umehluko omkhulu uma kuqhathaniswa nesilinganiso sokuqala ekuqaleni kocwaningo.
UDkt. Leitman wenze umbono wokuthi cishe ingxenye yeziguli ezinde ze-COVID zazinokukhubazeka kwenhliziyo ekuqaleni kocwaningo, njengoba kuboniswe yi-GLS.Noma kunjalo, bonke ababambiqhaza ocwaningweni babonise ingxenyena ye-ejection evamile, okuyisilinganiso esivamile esisetshenziselwa ukuhlola ukufinyela kwenhliziyo namandla okukhululeka ngesikhathi sokumpompa igazi.
UDkt. Leitman uphethe ngokuthi ingxenye ye-ejection iyodwa ayizweli ngokwanele ukukhomba iziguli ezinde ze-COVID okungenzeka ukuthi zinciphise ukusebenza kwenhliziyo.
Ukusetshenziswa kwe-oxygen therapy kungaba nezinzuzo ezingaba khona.
Ngokusho kukaDkt. Morgan, okutholwe kulolu cwaningo kusikisela ukuthambekela okuhle nge-hyperbaric oxygen therapy.
Kodwa-ke, weluleka ngokuqapha, esho ukuthi ukwelashwa kwe-oxygen hyperbaric akuyona ukwelashwa okwamukelekayo emhlabeni wonke futhi kudinga uphenyo olwengeziwe.Ukwengeza, kukhona ukukhathazeka mayelana nokwanda okungenzeka kwe-arrhythmias ngokusekelwe ocwaningweni oluthile.
UDkt. Leitman kanye nozakwabo baphethe ngokuthi ukwelashwa komoyampilo we-hyperbaric kungaba wusizo ezigulini ezine-COVID ende.Uphakamisa ukuthi ucwaningo olwengeziwe luyadingeka ukuze kutholakale ukuthi yiziphi iziguli ezingazuza kakhulu, kodwa kungaba yinzuzo kuzo zonke iziguli ezinde ze-COVID ukuthi zihlolwe uhlobo lwe-longitudinal longitudinal yomhlaba wonke futhi zicabangele ukwelashwa komoyampilo we-hyperbaric uma ukusebenza kwenhliziyo yazo kungasebenzi.
UDkt. Leitman uphinde uzwakalise ithemba lokuthi izifundo ezengeziwe zinganikeza imiphumela yesikhathi eside futhi zisize ochwepheshe bezokunakekelwa kwempilo ekunqumeni inani eliphelele lezikhathi ze-hyperbaric oxygen therapy.
Isikhathi sokuthumela: Aug-05-2023