Indima Ephawulekayo Ye-Hyperbaric Oxygen Therapy in Cardiovascular Health

Ukukhulula Amandla Okunikezwa Kweoksijini Okungokwenyama

Ucwaningo lubonisa ukuthi ngaphakathi kwe-hyperbaric chamber at 2 atmospheres of pressure(hyperbaric chamber 2 ata), ukunyibilika komoyampilo kufika izikhathi eziyishumi ezinkulu kunokucindezela okuvamile. Lokhu kumuncwa okuthuthukisiwe kwenza umoya-mpilo ungene ezindaweni ezivimbekile zokugeleza kwegazi, ekugcineni ulethe "umoya-mpilo ophuthumayo" enhliziyweni ye-ischemic noma izicubu zobuchopho. Lo mshini ufakazela ukuthi kunenzuzo ikakhulukazi kubantu abahlushwa yi-hypoxia engapheli ngenxa yezimo ezifana ne-coronary artery stenosis kanye ne-cerebral arteriosclerosis, enikeza ukukhululeka okusheshayo ezimpawini ezifana nokuqina kwesifuba kanye nesiyezi.

 

Ukuthuthukisa i-Angiogenesiskanye Nokwakha Kabusha Iziteshi Zomoya-mpilo

Ukwelashwa kwe-oxygen ye-hyperbaric akugcini nje ngokubhekana nezidingo ezisheshayo kodwa futhi kukhuthaza ukutakula isikhathi eside ngokugqugquzela ukukhululwa kwe-vascular endothelial growth factor (VEGF). Le nqubo isiza ekwakhekeni kokujikeleza kwesibambiso ezindaweni ze-ischemic, ithuthukisa kakhulu ukunikezwa kwegazi enhliziyweni nasengqondweni. Ucwaningo luye lwabonisa ukuthi ngemva kweseshini engu-20 ye-HBOT, iziguli ze-coronary artery disease zibone ukwanda okuphawulekayo kwe-myocardial microcirculation ngama-30% kuya ku-50%.

 

I-Anti-inflammatory and Antioxidant Effects: Ukuvikela Umsebenzi Weseli

Ngokungeziwe emandleni ayo okuhambisa umoya-mpilo, i-HBOT inemiphumela elwa nokuvuvukala kanye ne-antioxidant, iyenza ibaluleke kakhulu ekuvikeleni ukusebenza kwenhliziyo nobuchopho. Ucwaningo lubonisa ukuthi ukwelashwa kungacindezela izindlela zokuvuvukala ezifana ne-NF-κB, ukunciphisa ukukhululwa kwezinto ezibangela ukuvuvukala njenge-TNF-α ne-IL-6. Ngaphezu kwalokho, ukuthuthukiswa komsebenzi we-superoxide dismutase (SOD) kusiza ukuqeda ama-radicals mahhala, ukunciphisa ukulimala kwe-endothelial futhi kunikeze umphumela ovikelayo ezimweni ezingapheli zokuvuvukala njenge-atherosclerosis kanye nezinguquko ze-vascular ezihlobene nesifo sikashukela.

 

Izicelo Zomtholampilo ze-Hyperbaric Oxygen eZifo Zenhliziyo

Imicimbi Ye-Ischemic Enzima

I-Myocardial Infarction: Uma ilawulwa ngokuhambisana ne-thrombolysis noma imithi yokungenelela, i-HBOT inganciphisa ngokuphumelelayo i-apoptosis ye-myocardial cell futhi yehlise ingozi ye-arrhythmias eyingozi.

I-Cerebral Infarction: Ukusetshenziswa kwangaphambi kwesikhathi kwe-hyperbaric oxygen therapy kungandisa isikhathi sokusinda kwamangqamuzana, kunciphise usayizi we-infarct, futhi kuthuthukise ukusebenza kwezinzwa.

 

Ukuvuselelwa Kwezifo Ezingamahlalakhona

I-Stable Coronary Artery Disease: Iziguli zivame ukuzwa izimpawu ze-angina ezithuthukisiwe, ukubekezelelana okukhulayo kokuzivocavoca, nokunciphisa ukuncika emithini ye-nitrate.

I-Rapid Atrial Arrhythmias (Uhlobo Olunensayo): Ngemiphumela emibi ye-inotropic, i-HBOT isiza ukushaya kwenhliziyo kancane, inciphise ukusetshenziswa komoya-mpilo we-myocardial, futhi ithuthukise izimo ze-ischemic.

I-Hypertensive Heart Disease: Ukwelashwa kunciphisa i-viscosity yegazi futhi kunciphise i-hypertrophy ye-ventricular yesokunxele, ibambezele ngempumelelo ukuqhubeka kokuhluleka kwenhliziyo.

I-Post-Stroke Sequelae: Izinsiza ze-HBOT ekuhlelweni kabusha kwe-synaptic, ukuthuthukisa ukusebenza kwemoto kanye namakhono okuqonda.

 

Iphrofayili Yokuphepha Ye-Hyperbaric Oxygen Therapy

I-HBOT ngokuvamile ithathwa njengephephile, enemiphumela engemihle emincane. Ukukhathazeka okukhulu ngokuvamile kuwukungakhululeki kwengcindezi yendlebe, okungadanjiswa ngokulungiswa kwengcindezi. Kodwa-ke, kukhona ukungqubuzana okuqondile, okuhlanganisa ukopha okusebenzayo, i-pneumothorax engalashwa, i-emphysema enzima, i-pulmonary bulla, kanye nenhliziyo ephelele.

 

Amathemba Esikhathi esizayo: Ukusuka Ekwelapheni Kuya Ekuvinjelweni

Ucwaningo olusafufusa lugqamisa amandla e-HBOT ekubambezeleni inqubo ye-atherosclerotic ngokwenza ngcono ukunwebeka kwemithambo kanye nokwehlisa amazinga e-lipid egazi. Lokhu kubeka i-hyperbaric oxygen njengesinyathelo esisebenzayo sokulwa "ne-hypoxia ethule," ikakhulukazi kubantu abanezimpawu ezifana nesiyezi, ukuncipha kwenkumbulo, nokuqwasha. Ngokuthuthuka ekuthuthukisweni kokwelashwa okusizwa yi-AI kanye nezinhlelo ezintsha ezifana nokwelashwa kwe-stem cell, i-HBOT cishe isiseduze nokuba yisisekelo sokuphathwa kwezempilo yenhliziyo.

 

Isiphetho

Ukwelashwa kwe-oxygen ye-Hyperbaric kubonakala njengesixazululo esithembisayo, esingezona ezemithi zezifo zenhliziyo, esakhiwe ngesisekelo "sokunikezwa kwe-oksijeni ngokomzimba." Le ndlela ehlukahlukene, ehlanganisa ukulungiswa kwe-vascular, imiphumela elwa nokuvuvukala, kanye nezinzuzo ze-antioxidant, ibonisa izinzuzo ezinkulu kuzo zombili izimo eziphuthumayo eziphuthumayo kanye nokuvuselelwa okungapheli. Ngaphezu kwalokho, ukusetshenziswa kwe-electrocardiograms (ECG) njengenkomba ebucayi ye-oxygenation kanye ne-ischemia kungasebenza njengobufakazi bomtholampilo obubalulekile obusekela ukusebenza kwe-HBOT. Ukukhetha i-HBOT akukhona nje ukukhetha ukwelashwa; kusho ukuzibophezela okuqinile ekulawuleni impilo nokuphila kahle komuntu.